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Biomedical and Chemical Applications

2021-01-04  Click:[]

We have some collaborative works in the field of biomedical:

1.     Volumetric 3D analysis of high grade glioma at pre- and post-radiation therapy by magnetic resonance echo-planar spectroscopic imaging

 

 

31 patients with high grade glioma were recruited at both pre- and post-radiation therapy. 3D EPSI was employed on a Siemens 1.5 T scanner. NAA and Cho in lesion are normalized to Cr at contralateral part. At pre-radiation, Cho/Cr at lesion is significantly higher than that in contralateral part (p = 0.003). From pre- to post-radiation, Cho/Cr at lesion is significantly decreased (p < 0.007). Elevated Cho level can be an indicator for residual glioma tumor after surgery. Cho/Cr ratio can be used to monitor the treatment response. EPSI technique can be a promising way to monitor treatment response.

 

2.     Disturbance of thalamic metabolism and its association with regional neural dysfunction and cognitive impairment in minimal hepatic encephalopathy